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Exam 4 Intro to antibiotics Antibacterial & Antimicrobials Inhibit bacterial growth or kill the bacteria and microorganisms Antibacterial drugs may be used with other mechanisms to eliminate the infecting bacteria. For example, surgical procedures, dressing changes may also be performed along w/ the administration of an antibacterial agent Antibiotics Chemical produced by one kind of microorganisms that inhibit or kill another Antibacterials and antibacterial drugs Antibacterials have the help of the bodys natural defenses that help kill the bacteria as well Factors that impact immune function are: Age Nutrition Immunoglobulins Circulation, WBCs Organ function Antibacterial drugs have a different mechanism of action Inhibition of bacterial cell wall synthesis Alteration of membrane permeability Inhibition of protein synthesis Inhibition of synthesis of bacterial RNA and DNA Interference with metabolism within the cell Indications for antibiotics Prophylactic use Pts undergoing surgery STI exposure Prior to dental/procedures for pts at risk for prosthetic infection (heart valve, hip replacement) Recurrent UTIs Antibiotic mild allergic reaction Rash, pruritus, hives Antibiotic severe allergy: anaphylactic shock Bronchospasm, laryngeal edema, difficulty breathing, vascular collapse, cardiac arrest (emergency-stop antibiotic immediately) Antibiotic superinfection Secondary infection that occurs due to the unbalanced normal flora in the body. Antibiotics disrupt the normal microbiology Purchase document to see full attachment